JKMRS Volume 22, No 2, pp 34; Constructing Overhauser Dynamic ... | |
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2018년 06월 21일 / 조회수: 617 | |
Constructing Overhauser Dynamic Nuclear
Polarization-Nuclear Magnetic Resonance System Using Benchtop Electron Paramagnetic
Resonance Spectrometer
Seung-Bo Saun, JiWon Kim, and Oc Hee Han*
Western Seoul Center, Korea Basic Science Institute, Seoul
03759, Republic of Korea Abstract The Nuclear Magnetic Resonance
(NMR) technique using Dynamic Nuclear Polarization (DNP) procedures is
one of the promising techniques that enable overcoming low sensitivity problems
in NMR spectroscopy. We constructed an ODNP-NMR system using a commercial benchtop
EPR spectrometer. The 1H NMR peak area of water in aqueous solutions
of 4-hydroxy-TEMPO was enhanced more than 95 times in the ODNP-NMR experiments.
Our signal enhancement results were about 55% of the previously reported result.
This could be due to non-uniform microwave power over a sample and unwanted sample
heating by microwave. However, this portable ODNP-NMR spectrometer will be
eventually useful for site-specific detection with nano-scale spatial resolutions
and molecular dynamics studies with significantly improved signal sensitivity. |
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첨부파일 | 2.JKMRS_Han.pdf |