투고논문

Hyperpolarization Researches with Parahydrogen

Joongmoo Shim and Keunhong Jeong*

Department of Chemistry, Korea Military Academy, Seoul 01805, South Korea

Abstract Among several NMR hyperpolarization techniques, parahydrogen-based hyperpolarization technique is recently extensively utilized to enhance the sensitivity of the conventional NMR/MRI spectroscopy. Two mostly investigated research topics are PHIP (Parahydrogen Induced Polarization) and SABRE (Signal Amplification By Reversible Exchange), which are commonly using the parahydrogen as the source of hyperpolarization. Those researches have been considered as the promising techniques that could provide hyperpolarized states on the ambient substrates including biologically important materials. Therefore, based on their potentials, we briefly reviewed several important experimental results on those topics after introducing the basic principle of parahydrogen and its generation with conceptual explanations.

We hope this review will broaden the parahydrogen -based hyperpolarization transfer study on many researches in Korea.