|JKMRS Volume 21, No 4, pp 131; HMQC vs HSQC for Small Molecules|
|2017년 12월 21일 / 조회수: 226|
HMQC vs HSQC for Small Molecules
Eunhee Kim and Hae-Kap Cheong*
Protein Structure Group, Korea Basic Science Institute, Cheongju 28119, South Korea
Abstract Proton detected Heteronuclear Multiple Quantum Coherence (HMQC) and Heteronuclear Single Quantum Coherence (HSQC) essentially provide the same information – correlation of the chemical shift of the proton to J-coupled hetero nuclei such as 13C or 15N nuclei. This paper is a practical note for the students who ask which one is better and which methods they use routinely. Artifact suppression using phase cycling and gradient pulses are discussed.