JKMRS Volume 20, No 4, pp 138; Backbone Assignment of the N-te... | |
---|---|
2016년 12월 20일 / 조회수: 603 | |
Backbone Assignment of the N-terminal Domain of Human Replication Protein
A 70 kDa
Sungjin Lee and Chin-Ju Park*
Department of Chemistry, Gwangju Institute of Science
and Technology, Gwangju, 61005, South Korea Replication Protein A (RPA) is
the eukaryotic single-stranded DNA binding protein. It involves in DNA
replication, repair, and damage response. Among three subunits, RPA70 has a protein-protein
binding domain (RPA70N) at the N-terminal. It has known that the domain
recruits several damage response proteins to the damaged site. Also, it is suggested that there are more candidates that interact with RPA70N. Even though
several studies performed on the structural aspects of RPA70N and its ligand
binding, the backbone assignments of RPA70N is not available in public. In this
study, we present the backbone assignments of RPA70N. |
|
첨부파일 | 6. 박진주.pdf |