투고논문
| JKMRS Volume 20, No 2, pp 41;Bile acids from a Marine Sponge-A... | |
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| 2016년 06월 20일 / 조회수: 635 | |
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Bile acids from a Marine Sponge-Associated Fungus Penicillium sp.
Gam Bang Pil1,2, Ho Shik Won2 and Hee Jae Shin1,*
1Marine Natural Products Laboratory, Korea Institute of Ocean Science & Technology, Ansan, South Korea 2Department of chemistry & Applied Chemistry, Hanyang University, South Korea
Received Apr 6, 2016; Revised May 2, 2016; Accepted May 19, 2016
Abstract Chemical investigation of a marine-derived fungus, Penicillium sp. 108YD020, resulted in the discovery of six bile acid derivatives, glycocholic acid (1), glycocholic acid methyl ester (2), cholic acid (3), glycochenodeoxycholic acid (4), glycodeoxycholic acid methyl ester (5), and cholic acid methyl ester (6). The structures of six bile acid derivatives 1–6 were determined by the detailed analysis of 1D, 2D NMR and LC-MS data, along with chemical methods and literature data analysis. Keywords Marine natural products, cholic acid, glycocholic acid, bile acids, marine fungus, Penicillium sp. |
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| 첨부파일 | 2신희재.pdf |