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JKMRS Volume 24, No 4, pp 123, Chemical Constituents Isolated ...
2020년 12월 20일 / 조회수: 201

Chemical Constituents Isolated from the Moss-derived Fungus
Talaromyces sp.

 

 

Hoseong Hwang, Hak Cheol Kwon, Jaeyoung Kwon*

 

 

Natural Product Informatics Research Center, Gangneung Institute of Natural Products, Korea Institute of Science and Technology (KIST), Gangneung 25451, Republic of Korea

 

 

 

 

Received Dec 13, 2020; Revised Dec 14, 2020; Accepted Dec 15, 2020

 


Abstract All plants in natural ecosystems are living in symbiosis with endophytes. Recently, there has been an increasing interest in endophytes since these organisms can interact with the hosts and produce various structurally or biologically interesting molecules. This study aimed to identify these molecules from endophytes. Chemical investigation of Climacium dendroides-derived fungus Talaromyces sp. resulted in the isolation of two diphenyl ether derivatives, purpactin A (1) and penicillide (2), and two steroids, dankasterone A (3) and calvasterol B (4). The structures of the compounds were identified via extensive spectroscopic and spectrometric methods. Four compounds did not show any antioxidative activities in the on-line antioxidant activity screening system.

 

Keywords bryophyte, fungi, Talaromyces sp., diphenyl ether derivative, steroid

 

* Address correspondence to: Jaeyoung Kwon, Natural Product Informatics Research Center, Gangneung Institute of Natural Products, Korea Institute of Science and Technology (KIST), Gangneung 25451, Republic of Korea, Tel: +82-33-650-3516; E-mail: kjy1207@kist.re.kr

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